A study, published in Psychopharmacology, examined how CBN and CBD affect feeding patterns and appetite in rats. This is one of the few studies that explore the appetizing effects of cannabinoids, other than THC, which is know for its power in that regard.

Rats were satiated before they were administered CBD and CBN.

The study found that CBN also acts as a catalyst for appetite by significantly decreasing the latency to feed. Furthermore, consummatory behavior was heightened, as CBN increased the size of meal 1 and its duration, as well as the food intake both during the first hour and throughout the entire test. The increase in food intake, compared to the one in regular circumstances, was particularly pronounced after the first meal.

These findings clearly show that CBN increases appetite, possibly dramatically. What’s more interesting is that the appetite seems to grow after the first meal, at least in comparison with rats’ regular appetite after meal 1.

As CBN is a non-psychoactive alternative to THC, these findings could prove highly beneficial for medical patients who struggle with eating, for example as a result of chemotherapy, and don’t want to or simply can’t rely on psychoactive cannabinoids like THC for a boost in appetite.